Mount Sinai study links prenatal acetaminophen to higher autism, ADHD risk
Why it matters
A gold-standard Navigation Guide review across 46 studies and 100,000+ participants is exactly the kind of peer-reviewed source that moved the acetaminophen question from fringe to front-page.
Researchers at the Icahn School of Medicine at Mount Sinai found that prenatal exposure to acetaminophen may increase the risk of neurodevelopmental disorders, including autism spectrum disorder and ADHD. The study, published in BMC Environmental Health, is the first to apply the rigorous Navigation Guide methodology to this literature.
Acetaminophen is the most commonly used over-the-counter pain and fever medication during pregnancy, used by more than half of pregnant women worldwide. The Mount Sinai-led analysis of 46 studies incorporating data from more than 100,000 participants challenges the perception that it is uniformly safe and underscores the need for both caution and further study.
The Navigation Guide Systematic Review methodology is a gold-standard framework for synthesizing and evaluating environmental health data, allowing researchers to rate each study’s risk of bias and the strength of the evidence individually and collectively.
Source
Mount Sinai NewsroomRelated coverage
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